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Famotidine polymorphic transformation in the grinding ...

The raw material of famotidine form B powder (water content: 0.07%, w/w) was respectively ground for 30 min in an oscillatory ball mill (Mixer Mill MM301, Retsch & Co., Germany) at an oscillation frequency of 20 Hz. Each 0.2 g form B powder was placed in a 10 ml volume agate milling jar containing two 10 mm diameter agate balls.

2010 2, 30-49; doi:10.3390/pharmaceutics2010030 …

2.2.1. Sample preparation by ball milling (cold room) The drugs were milled using an oscillatory ball mill (Mixer Mill MM301, Retsch & Co., Germany). A central composite face centered design was used for the milling experiments for both compounds. The experimental design was created using MODDE software (version 7, Umetrics AB, Sweden).

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Mixer Mill MM 301. Retsch mixer mills MM 301 are particularly suited for dry and wet grinding of small quantities of material. The mills are ideal for mixing and …

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Operating Instructions for Oscillating Mill MM 200 © Retsch , 42781 Haan, Rheinische Str.36, Germany Doc.Nr. D 98.746.9999

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RETSCH is the world leading manufacturer of laboratory ball mills and offers the perfect product for each application. The High Energy Ball Mill E max and MM 500 were developed for grinding with the highest energy input. The innovative design of both, the mills and the grinding jars, allows for continuous grinding down to the nano range in the shortest amount of time - with only minor warming ...

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An oscillatory ball mill (Mixer Mill MM301, Retsch & Co., Germany) was used for cryo milling as follows: 1 g of indomethacin was placed into a 25 mL milling jar and milled with two 12 mm balls for 120 minutes. The jars were immersed in liquid nitrogen for 3 min before milling and repeatedly for 3 min at 15 min intervals.

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21.05.2004 Retsch & Co. KG 2 Doc.no. D 98.741.9999 Notes on the operating instructions These operating instructions for the type MM 301 laboratory vibration mill provide all the necessary information on the topics named in the

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Retsch Mm400 Ball Mill Machine Mining. Retsch Mm400 Ball Mill. We are a professional mining machinery manufacturer, the main equipment including: jaw crusher, cone crusher Page 1 Operating Instructions for Oscillating Mill MM400 Retsch 42781 Haan RetschAllee 15 Germany 282012 0002 Page 2 Notes on these operating instructions These ...

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The Mixer Mill MM 400 is a compact, versatile bench-top unit developed specially for dry, wet and cryogenic grinding of small sample amounts. This laboratory mill mixes and homogenizes up to 2 x 20 ml powders and suspensions within a few seconds.

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These mixer mills grind, mix, or homogenize 2 samples from 0.2 ml up to 20 ml in a single operation or process up to 20 samples for cell disruption. Mixer Mill MM 200 Range of grinding jars Mixer Mill MM 301 MM 200 MM 301 Sample volume max. 2 x 10 ml 2 x 20 ml Feed grain size max. 6 mm 8 mm Final fineness down to < 10 µ 5 m< m

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Laboratory Mills, Crushers and Sieve Shakers. RETSCH is the leading solution provider for neutral-to-analysis sample preparation and characterization of solids. Based on a century of experience RETSCH develops size reduction and sieving equipment which is characterized by excellent performance, operating convenience, safety and a long lifetime.

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The widest ball mills in RETSCH's comprehensive range of ball mills comprises High Energy Ball Mills, Planetary Ball Mills and Mixer Mills. Whereas the Mixer Mills are used for dry/wet/cryogenic grinding and homogenizing small sample volumes, the Planetary Ball Mills meet and exceed all requirements for fast and reproducible Wet grinding Dry grinding Grind size Adapters for disposable vials ...